early detection of GIST

Spearheaded by Stephen Fry, who was diagnosed and treated for prostate cancer a few years ago, the NHS has launched a campaign to encourage people with cancer symptoms to come forward for a potentially lifesaving check-up.

The impact of COVID on the NHS and how we interact with it has been profound and recent research indicated that three in five people are concerned about burdening the NHS, with 49% saying they would currently delay seeking medical advice. This is particularly concerning when it comes to cancer as, in most cases, early detection is key to successful treatment.

In a recent video, Stephen and other cancer sufferers talk the symptoms they’d experienced and what prompted them to visit their GP or cancer specialist. Alongside more common cancers, Sarah talked about her experience after being diagnosed with a GIST, or tumour in her small intestine.

What are the symptoms of GIST you should be looking out for?

Often you may not experience any symptoms in the early stages of the disease. Signs of a GIST may include:

  • Abdominal discomfort or pain
  • A lump or mass in the abdomen that you can feel
  • Vomiting
  • Blood in your stools or vomit
  • Fatigue due to anaemia
  • Feeling full after eating just a small amount
  • Loss of appetite or marked weight loss

GIST is a much less well known form of cancer so, as Mr Myles Smith, Consultant Surgical Oncologist at the Royal Marsden comments. “It’s great to see the @NHS and @GISTUK raising awareness of early detection of cancer, and GIST in the UK.”

For more advice on the symptoms of GIST and treatment options, call 020 7808 2785 to arrange a consultation.

Lipoma

Finding a lump on your body can be terrifying. However, the good news is that not all lumps are a sign of cancer. It could be that you have a Lipoma, the most common type of tumour to grow underneath the skin. While it is classed as a tumour, it isn’t harmful.

So, what is a Lipoma and how can you tell it apart from a cancerous tumour? Discover everything you need to know below…

What is a Lipoma?

A Lipoma is a fatty lump that develops within the soft tissue. It is estimated that 1 out of 1000 people will get a Lipoma at some stage in their lives. They are commonly found on the thighs, upper body, and arms.

It isn’t known what causes a Lipoma to develop. However, it is known to be genetically linked and more prominent in those who are middle-aged.

Lipoma symptoms to watch out for

If you have a Lipoma, you’ll notice the following symptoms:

  • The lump will be small and soft
  • It moves easily under the skin when you touch it
  • It won’t cause you pain
  • The lump will be just underneath the skin

Most Lipomas are less than 2 inches in diameter. However, it is possible for them to grow larger. You may also notice you have more than one at a time. Perhaps the most important factor to look out for is whether it is soft and easily movable. Cancer lumps are typically very hard, and you won’t be able to move them with finger pressure alone.

Most of the time Lipomas are also painless. However, as they grow, they may push on nearby blood vessels or nerves.  Although these symptoms do suggest that you have a Lipoma and nothing more serious, it is still extremely important to get any lump checked out by the doctor.

Diagnosing a Lipoma

A physical exam is usually all that is needed to diagnose a Lipoma. However, in some cases, a biopsy may need to be carried out. This involves removing a small part of the lump before it is analysed under a microscope. Other tests such as ultrasound, MRI’s and sometimes CT scans may also help to diagnose a Lipoma.

If you are diagnosed with Lipoma, you won’t necessarily need treatment. However, the tumour won’t just magically go away. Therefore, if it is causing cosmetic issues, you can choose to have it removed.

All lumps should be diagnosed as quickly as possible. That way, if it does turn out to be something more harmful, treatment can be undertaken quickly. So if you have a lump that is over 5cm in diameter, book a visit to the One-Stop Lump Clinic with Mr Smith (with or without a letter from your GP).

Go to – https://surgicaloncology.co.uk/one-stop-cancer-clinic/ and use the form here to give us more information about the lump and any symptoms you are experiencing. Then we can arrange an Ultrasound or MRI in either the Chelsea Outpatient Centre or the Chiswick Medical Centre.

soft tissue sarcomas

Soft tissue sarcomas are a type of uncommon cancer that develops within connective or supportive tissues. These include muscles, tendons, fibrous and fatty tissue, blood vessels and nerves. They are most commonly found in the legs, arms and trunk of the body.

It is important to detect soft tissue sarcomas as quickly as possible, to access good quality care and reduce problems the tumour may cause. There are different types of soft tissue sarcomas and some will be more aggressive than others. For this reason, it is important to seek early detection to identify the type and severity of the condition and to reduce the potential impact of treatment.

Here, we’ll look at why it is important to detect soft tissue sarcomas early and the treatments available.

Why is early detection important?

It is estimated that around 15 people are diagnosed with sarcoma each day within the UK. This means approximately 5,300 people develop them each year. There are over 100 different types of sarcomas, with soft tissue sarcomas being the most common.

Soft tissue sarcomas account for 88% of sarcomas in the UK. There are many different types including:

  • Extremity (limb and trunk)
  • Gastrointestinal stromal tumours (GISTs)
  • Retroperitoneal sarcomas (occur deep in the abdomen and pelvis)
  • Gynaecological sarcomas (occur in the female reproductive system)

Whichever type of soft tissue sarcoma you have, early diagnosis is helpful.

Signs and symptoms to watch out for

If you stand any chance of diagnosing sarcomas early, you need to know the signs and symptoms to watch out for. These can vary depending upon the size and location of the tumour.

One of the first symptoms you may notice is a lump or swelling within the soft tissue. The lump may be getting bigger, and it is usually painful although not all patients experience pain.

Ideally, the diagnosis should be provided when the lump is under 5cm in size. So, being aware of any lumps that develop and monitoring them for any change is going to help you to ensure you catch it early. The NHS recommends assessment of any lump that is greater than 5cm, deep, rapidly growing, painful or recurrent.

Diagnosis will typically consist of a physical examination, taking scans and a biopsy. Ultrasounds, MRIs and sometimes CT scans may all be used to diagnose sarcoma.

How are soft tissue sarcomas managed and treated?

Surgery is typically the most common treatment for soft tissue sarcomas, often with radiotherapy to reduce the risk of recurrence. Overall, the outcomes are positive.

Several types of surgery can be carried out to treat these types of cancer, depending on the size and location of the tumour. The surgeon will go through your options and discuss which one would be better suited to you. It is important to understand the risks and complications involved with each type of surgery. The aim of surgery is to potentially cure the cancer, and certainly to control it at that site.

Overall, early detection of soft tissue sarcomas is helpful to ensure effective treatment. Watching out for the signs will help you to seek a diagnosis quickly. There are several treatment options available, with surgery being the most effective.

For more advice, call us on 020 3770 5864 to arrange an appointment at the HCA Lister Hospital Clinics (Chelsea Outpatient Centre and Chiswick Medical Centre) or call 020 7808 2785 to book a consultation with Mr Myles Smith at the Royal Marsden Hospital.

Gastrointestinal leiomyosarcoma

Surgical oncologist Mr Myles Smith and colleagues recently published a new study in the European Journal of Surgical Oncology entitled ‘Gastrointestinal leiomyosarcoma demonstrate a predilection for distant recurrence and poor response to systemic treatments’.

Primary leiomyosarcoma (LMS tumour) of the gastrointestinal (GI) tract is rare and there is currently limited literature on the outcome for patients. The team at the Royal Marsden Hospital followed 46 patients with a median age of 54 years who underwent treatment. They concluded that the ‘risk of recurrence is significant’ and that there needed to be the development of ‘more effective systemic therapies for metastatic disease.

lump removal surgery

Trying to decide whether to have lump removal surgery? While the majority of lumps are harmless, occasionally they can be a sign of a serious underlying issue.

Knowing when to remove a lump is important when it comes to protecting your health. The only real way to determine whether your lump should be removed is by having it assessed by a professional.

Below, you will discover the characteristics of some of the most common types of lumps and whether they typically need to be removed. You will also learn more about the symptoms that should be investigated further.

What characteristics do harmless lumps have?

Although some lumps can be cancerous, the truth is, most are completely harmless. The question is, how do you know the difference?

When it comes to harmless lumps, they do tend to have a few characteristics in common. They are usually soft to touch and remain mobile when touched. That is, they move around when you touch them, rather than stay in the same position. They are also typically located in the fat layer of the skin.

Common conditions which can lead to the development of harmless lumps include cysts, tendonitis, rheumatoid arthritis, and enlarged lymph nodes. There is usually an explanation for the lump such as a trauma, and they will get better over time.

The characteristics of harmful lumps

With more harmful lumps, they too have a few characteristics you should look out for.

To be assessed, a lump may measure more than 5cm or be growing rapidly. It could also be located deep under the skin, or it may be recurrent. These symptoms can point to a lump that needs to be investigated in case it could represent a soft tissue tumour. In these cases, you may require a further assessment from a specialist soft tissue cancer expert.

While finding a lump can be alarming, most will not turn out to be worrisome. With that being said, even benign lumps can cause potential health issues, so it is best to book a consultation to talk through your lump removal surgery options.

You can book an appointment with Mr Myles Smith at the One-Stop Lump Clinic with or without a GP letter. Use the form on the Clinic website to provide information about the lump and any symptoms you are experiencing. From there we can arrange an Ultrasound or MRI in either the Chelsea Outpatient Centre or the Chiswick Medical Centre.

liposarcomas

Sarcomas are a type of cancer that develops within the body’s connective tissues. These include fat, bone, and muscle. While these types of cancer only account for around 1% of all cases, there are over 50 different subtypes, including liposarcomas.

Here, we look at what liposarcomas are, and the different treatment options.

What are liposarcomas?

Liposarcomas are rare tumours that develop from fat tissue which occurs within the soft tissues of the body. They are classified as cancer due to their ability to reoccur and spread within other areas of the body.

There are different subtypes of liposarcomas, and the severity of the disease will depend upon the type experienced. It tends to develop more within the body’s extremities such as the thigh. However, it can also occur in other areas such as at the back of the abdomen.

Liposarcomas are more present in middle-aged men aged 50-65. They are also extremely rare in children. The three main types of liposarcomas are:

  • Atypical Lipomatous or well-differentiated/dedifferentiated
  • Myxoid round cell
  • Pleomorphic

Atypical lipomatous liposarcomas are locally aggressive and present as painless masses deeper in the tissues, but we believe they do not spread elsewhere unless they transform to a dedifferentiated liposarcoma. The myxoid round cell and pleomorphic types are mostly found in the legs and arms and carry a risk of recurring in other sites.

Signs and symptoms to watch out for

In the early stages of a liposarcoma, you may not experience any symptoms. It is common that you do not experience any symptoms until the tumour has grown large enough to compress nearby tissues.

The exact symptoms will depend upon where the tumour is, alongside how large it is. You may also be able to feel the liposarcoma as a deep mass.

To diagnose the liposarcoma, an MRI and possibly a core biopsy will be performed.

Liposarcoma treatment options

The main treatment for liposarcomas is surgery. Several different types of surgery can be done, depending on the size and location of the tumour. You may also need to undergo radiotherapy alongside the surgery, either before or after. This would help to reduce the risk of recurrence. Mr Smith will go through your options in your consultation and discuss which treatment would be better suited to you.

After treatment has been provided, routine follow-ups will be attended. This will help to ensure that the liposarcoma doesn’t come back. If it does, treatment will be able to be provided quickly.

Liposarcomas are fairly rare, but they are known to reoccur. Early detection is the best way to ensure diagnosis and effective treatment, and there are several options including surgery.

For more advice, call us on 020 3770 5864 to arrange an appointment at the HCA Lister Hospital Clinics (Chelsea Outpatient Centre and Chiswick Medical Centre) or call 020 3770 5864 to book a consultation with Mr Myles Smith at the Royal Marsden Hospital.

Sarcoma FAQs

Like any form of cancer, spotting the signs of sarcoma early is crucial. To help spread awareness, 28-year-old Gareth Emmerson is cycling a whopping 1000 miles across the UK. A Sarcoma sufferer, Gareth is a true inspiration, and has exceeded his fundraising target of £100,000 for Sarcoma UK!

As last month marked Sarcoma Awareness Month, we thought we would share some common questions. For example, what is it? And how is it treated? Therefore, you can find out everything you need to know below.

Sarcoma FAQs: What is sarcoma?

Sarcoma is a term used to describe a broad group of uncommon cancers. It is estimated that there are around 100 different types of sarcomas, separated into three distinct categories. These include primary bone sarcoma, soft tissue sarcoma, and gastro-intestinal stromal tumours.

They can develop within the bone, cartilage, muscles, nerves, fibrous and fatty tissues. They most commonly develop around the legs, trunk, and arms. There are approximately 5300 cases of sarcomas diagnosed each year in the UK. They account for fewer than 1% of adult cancer cases in the country.

The most common type of sarcoma patients develop is soft tissue sarcoma. This includes liposarcoma, undifferentiated pleomorphic sarcoma, and leiomyosarcoma soft tissue sarcomas.

Sarcoma FAQs: How is it diagnosed?

Getting an early diagnosis is key for successful treatment of sarcoma. The main symptom you may experience is a lump in the arm, leg, or trunk area. While these are the most common areas for them to develop, they can occur in other parts of the body too.

There are several ways to diagnose the condition, starting with a clinical assessment. A scan, such as an X-Ray, Ultrasound, MRI, or CT scan, will help to see whether there is a sarcoma inside the body. A biopsy may need to be carried out on suspected tissue.

If sarcoma is diagnosed, it will be presented as a specific grade and stage. There are three grades, including low, intermediate, and high-grade. The latter is the fastest spreading, more aggressive form of the condition. In addition, it will be categorised into one of four stages. Stage 1 is the easiest to treat as the cancer is localised. Stage 4 cancer is the most severe, highlighting that it has spread throughout the body.

Sarcoma FAQs: What treatment options are available?

The subtype, grade and stage of your sarcoma will determine the type of treatment you require. Whichever type you have, it should be treated at a specialist centre.

The most common type of treatment is a combination of surgery and radiotherapy. The tumour is removed, alongside additional tissue in the surrounding area. This prevents any cancer cells potentially being left behind. But if the tumour is large, radiotherapy can be used to shrink it down prior to surgery. Certainly it reduces the risk of the tumour recurring.

You will learn which treatment method is right for you after receiving a diagnosis. In addition, you may be offered the opportunity to take part in clinical trials.

Above all, if you are worried you may have sarcoma, you should seek a diagnosis as quickly as possible. The earlier it is caught, the easier it will be to treat.

For more advice, call us on 020 3770 5864 to arrange an appointment at the HCA Lister Hospital (Chelsea Outpatient Centre and Chiswick Medical Centre). Or call 020 7808 2785 to book a consultation with Mr Myles Smith at the Royal Marsden Hospital.

Sarcoma Awareness

As a specialist in Sarcoma surgery, Mr Myles Smith supports the recently launched Loneliest Cancer campaign (#TheLoneliestCancer), from Sarcoma UK, to raise awareness of a cancer few have heard of.  There are many issues with a cancer that many have no knowledge of, and although the majority of patients are successfully treated, they may have unique challenges to overcome.  Some include physical and mental barriers that may be isolating.  Sarcoma UK (@SarcomaUK) invests in research, support and increasing awareness of Sarcoma in the UK and internationally.

treatment of sarcomas

At the recent Chemotherapy Foundation Symposium, speaker Dr Andrew Wagner, medical director of ambulatory oncology at the Dana-Farber Cancer Institute and assistant professor of medicine at Harvard Medical School, explained that the treatment of sarcomas is rapidly evolving as therapies are increasingly being matched to specific molecularly defined histologies.

“As with other cancers, we have to look at every patient as an individual, putting into context their comorbidities, the location of their tumor, the subtype and grade of the tumor, and the tumor’s growth pattern — meaning, does it have more indolent behavior or more aggressive behavior?” Wagner commented.

sarcoma surgery

A cancer survivor has recently published an incredible photo diary detailing how her face was rebuilt following an operation to remove a sarcoma from her upper jaw and eye socket.

Jen Taylor found out she had cancer after going to the dentist: “I had no pain, I could just feel something on the front of my face. There was a lump behind my nose and teeth, but it was too big to be a spot – maybe the size of a grape.” As well as the physical scars, she also initially lost the ability to eat, drink and talk and had to relearn these skills after undergoing sarcoma surgery. Jen is now free of cancer after having chemotherapy.